diff --git a/packages/js/internal-style-build/index.js b/packages/js/internal-style-build/index.js
index e7d93fc8431..ccf4b5eda23 100644
--- a/packages/js/internal-style-build/index.js
+++ b/packages/js/internal-style-build/index.js
@@ -21,7 +21,11 @@ module.exports = {
 		rules: [
 			{
 				test: /\.s?css$/,
-				exclude: [ /storybook\/wordpress/, /build-style\/*\/*.css/ ],
+				exclude: [
+					/storybook\/wordpress/,
+					/build-style\/*\/*.css/,
+					/[\/\\](changelog|bin|docs|build|build-module|build-types|vendor|tests|test)[\/\\]/,
+				],
 				use: [
 					MiniCssExtractPlugin.loader,
 					'css-loader',
diff --git a/plugins/woo-ai/changelog/dev-webpack-loaders-scannig-paths-tweaks b/plugins/woo-ai/changelog/dev-webpack-loaders-scannig-paths-tweaks
new file mode 100644
index 00000000000..30f765e3fca
--- /dev/null
+++ b/plugins/woo-ai/changelog/dev-webpack-loaders-scannig-paths-tweaks
@@ -0,0 +1,4 @@
+Significance: patch
+Type: dev
+
+Monorepo: tweak Webpack loaders paths filtering for better build perfromance.
diff --git a/plugins/woo-ai/webpack.config.js b/plugins/woo-ai/webpack.config.js
index d131f0792b0..24355a5325a 100644
--- a/plugins/woo-ai/webpack.config.js
+++ b/plugins/woo-ai/webpack.config.js
@@ -1,5 +1,6 @@
 const defaultConfig = require( '@wordpress/scripts/config/webpack.config' );
 const WooCommerceDependencyExtractionWebpackPlugin = require( '@woocommerce/dependency-extraction-webpack-plugin' );
+const path = require( 'path' );
 
 module.exports = {
 	...defaultConfig,
@@ -13,7 +14,7 @@ module.exports = {
 			{
 				test: /\.tsx?$/,
 				use: 'ts-loader',
-				exclude: /node_modules/,
+				include: [ path.resolve( __dirname, './src/' ) ],
 			},
 			{
 				test: /\.(png|jp(e*)g|svg|gif)$/,
diff --git a/plugins/woocommerce-admin/webpack.config.js b/plugins/woocommerce-admin/webpack.config.js
index d259661f391..649d22749c3 100644
--- a/plugins/woocommerce-admin/webpack.config.js
+++ b/plugins/woocommerce-admin/webpack.config.js
@@ -126,8 +126,8 @@ const webpackConfig = {
 					amd: false,
 				},
 				exclude: [
-					// Exclude node_modules/.pnpm
-					/node_modules(\/|\\)\.pnpm(\/|\\)/,
+					/[\/\\]node_modules[\/\\]\.pnpm[\/\\]/,
+					/[\/\\](changelog|bin|build|docs|test)[\/\\]/,
 				],
 				use: {
 					loader: 'babel-loader',
diff --git a/plugins/woocommerce-beta-tester/changelog/dev-webpack-loaders-scannig-paths-tweaks b/plugins/woocommerce-beta-tester/changelog/dev-webpack-loaders-scannig-paths-tweaks
new file mode 100644
index 00000000000..30f765e3fca
--- /dev/null
+++ b/plugins/woocommerce-beta-tester/changelog/dev-webpack-loaders-scannig-paths-tweaks
@@ -0,0 +1,4 @@
+Significance: patch
+Type: dev
+
+Monorepo: tweak Webpack loaders paths filtering for better build perfromance.
diff --git a/plugins/woocommerce-beta-tester/webpack.config.js b/plugins/woocommerce-beta-tester/webpack.config.js
index e7fff48497a..76b4f828e0c 100644
--- a/plugins/woocommerce-beta-tester/webpack.config.js
+++ b/plugins/woocommerce-beta-tester/webpack.config.js
@@ -1,5 +1,6 @@
 const defaultConfig = require( '@wordpress/scripts/config/webpack.config' );
 const WooCommerceDependencyExtractionWebpackPlugin = require( '@woocommerce/dependency-extraction-webpack-plugin' );
+const path = require( 'path' );
 
 module.exports = {
 	...defaultConfig,
@@ -15,7 +16,7 @@ module.exports = {
 			{
 				test: /\.tsx?$/,
 				use: 'ts-loader',
-				exclude: /node_modules/,
+				include: [ path.resolve( __dirname, './src/' ) ],
 			},
 		],
 	},
diff --git a/plugins/woocommerce-blocks/bin/webpack-configs.js b/plugins/woocommerce-blocks/bin/webpack-configs.js
index 21e0fdccb4a..532ad61a231 100644
--- a/plugins/woocommerce-blocks/bin/webpack-configs.js
+++ b/plugins/woocommerce-blocks/bin/webpack-configs.js
@@ -43,7 +43,7 @@ const getSharedPlugins = ( {
 	[
 		CHECK_CIRCULAR_DEPS === 'true' && checkCircularDeps !== false
 			? new CircularDependencyPlugin( {
-					exclude: /node_modules/,
+					exclude: [ /[\/\\](node_modules|build|docs|vendor)[\/\\]/ ],
 					cwd: process.cwd(),
 					failOnError: 'warn',
 			  } )
@@ -94,7 +94,9 @@ const getCoreConfig = ( options = {} ) => {
 			rules: [
 				{
 					test: /\.(t|j)sx?$/,
-					exclude: /node_modules/,
+					exclude: [
+						/[\/\\](node_modules|build|docs|bin|storybook|tests|test)[\/\\]/,
+					],
 					use: {
 						loader: 'babel-loader',
 						options: {
@@ -208,7 +210,7 @@ const getMainConfig = ( options = {} ) => {
 			rules: [
 				{
 					test: /\.(j|t)sx?$/,
-					exclude: /node_modules/,
+					exclude: [ /[\/\\](node_modules|build|docs|vendor)[\/\\]/ ],
 					use: {
 						loader: 'babel-loader',
 						options: {
@@ -349,7 +351,7 @@ const getFrontConfig = ( options = {} ) => {
 			rules: [
 				{
 					test: /\.(j|t)sx?$/,
-					exclude: /node_modules/,
+					exclude: [ /[\/\\](node_modules|build|docs|vendor)[\/\\]/ ],
 					use: {
 						loader: 'babel-loader',
 						options: {
@@ -471,7 +473,7 @@ const getPaymentsConfig = ( options = {} ) => {
 			rules: [
 				{
 					test: /\.(j|t)sx?$/,
-					exclude: /node_modules/,
+					exclude: [ /[\/\\](node_modules|build|docs|vendor)[\/\\]/ ],
 					use: {
 						loader: 'babel-loader',
 						options: {
@@ -582,7 +584,7 @@ const getExtensionsConfig = ( options = {} ) => {
 			rules: [
 				{
 					test: /\.(j|t)sx?$/,
-					exclude: /node_modules/,
+					exclude: [ /[\/\\](node_modules|build|docs|vendor)[\/\\]/ ],
 					use: {
 						loader: 'babel-loader',
 						options: {
@@ -693,7 +695,7 @@ const getSiteEditorConfig = ( options = {} ) => {
 			rules: [
 				{
 					test: /\.(j|t)sx?$/,
-					exclude: /node_modules/,
+					exclude: [ /[\/\\](node_modules|build|docs|vendor)[\/\\]/ ],
 					use: {
 						loader: 'babel-loader',
 						options: {
@@ -856,6 +858,7 @@ const getStylingConfig = ( options = {} ) => {
 			rules: [
 				{
 					test: /\.(j|t)sx?$/,
+					exclude: [ /[\/\\](node_modules|build|docs|vendor)[\/\\]/ ],
 					use: {
 						loader: 'babel-loader',
 						options: {
@@ -976,7 +979,7 @@ const getInteractivityAPIConfig = ( options = {} ) => {
 			rules: [
 				{
 					test: /\.(j|t)sx?$/,
-					exclude: /node_modules/,
+					exclude: [ /[\/\\](node_modules|build|docs|vendor)[\/\\]/ ],
 					use: [
 						{
 							loader: require.resolve( 'babel-loader' ),
@@ -1062,7 +1065,7 @@ const getCartAndCheckoutFrontendConfig = ( options = {} ) => {
 			rules: [
 				{
 					test: /\.(j|t)sx?$/,
-					exclude: /node_modules/,
+					exclude: [ /[\/\\](node_modules|build|docs|vendor)[\/\\]/ ],
 					use: {
 						loader: 'babel-loader',
 						options: {
diff --git a/plugins/woocommerce/changelog/dev-webpack-loaders-scannig-paths-tweaks b/plugins/woocommerce/changelog/dev-webpack-loaders-scannig-paths-tweaks
new file mode 100644
index 00000000000..30f765e3fca
--- /dev/null
+++ b/plugins/woocommerce/changelog/dev-webpack-loaders-scannig-paths-tweaks
@@ -0,0 +1,4 @@
+Significance: patch
+Type: dev
+
+Monorepo: tweak Webpack loaders paths filtering for better build perfromance.